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Welcome to the website for the Laboratory for Innovative Clinical Trials (LICT).

The University of North Carolina (UNC) at Chapel Hill has established the Laboratory for Innovative Clinical Trials (LICT) in 2007. Clinical trials are controlled studies that test the relative benefits of various treatments, such as drugs, surgery, or interventions in human beings.

Building on the research strength of its biostatistics faculty who are highly engaged in various areas of methodological and applied research in clinical trials, the LICT has become a global leader in research development in the design and conduct of clinical trials.

The LICT is led by Dr. Joseph G. Ibrahim, Alumni Distinguished Professor of Biostatistics in the Department of Biostatistics and Director of the Biostatistics Core at the Lineberger Comprehensive Cancer Center (LCCC). The LICT has an interdisciplinary focus and theme, in which faculty from several departments at UNC as well as collaborators from industry engage in both methodologic and applied research in clinical trials design, analysis, and evaluation.

The main mission of the LICT is to develop, as well as integrate, methodologic and applied  research for the design and analysis of clinical trials. By building on UNC’s reputation and  excellence in translational research, one of the primary goals of the LICT is to advance statistical science in clinical trials and quickly move it forward into clinical and statistical  practice. One of the unique strengths of the LICT is the ability to nicely balance  methodological and collaborative research in clinical trials by building highly interdisciplinary and integrated research teams that  are capable of producing  new methodology and putting it into clinical and statistical practice.

The development of the LICT was facilitated by the Gillings Gift to The Gillings School of Global Public Health (SPGH).