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One of the unique aspects of the LICT is the development of methodologic research in clinical trials to advance statistical science in this area. Methodologic research areas include novel methods for

  • design and joint evaluation of efficacy and safety in phase II clinical trials

  • innovative methods for interim monitoring; adaptive methods for the design of phase II and III clinical trials

  • missing data

  • meta-analysis and network meta-analysis

  • subgroup analysis

  • survival analysis

  • longitudinal data

  • Bayesian methods for clinical trial design and analysis